Staff Information
DR ANDREW FELLOWES MSc (Hons), Ph.D
Section Head, Molecular Pathology
Phone : 03 364 0300 Ex 80551
Fax : 03 364 0545
EMail : andrew.fellowes@cdhb.govt.nz

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After completing an MSc (Hons) at Canterbury University's Plant and Microbial Sciences Department, Andrew moved to the Christchurch School of Medicine to look at mutations in the apo E gene involved in hyperlipidaemia. He joined Canterbury Health Laboratories in 1989 and now has over 10 years experience in mutational analysis in human genetic disease. Andrew completed his Ph.D in 2000.

Publications

  1. Blacklock HA. ,Case J. ,Chan T. ,Raizis AM ,FELLOWES AP. ,Brennan SO ,George PM ,et al.
    ",Novel sequence insertion in a Maori patient with transfusion-dependent beta-thalassaemia.
    Br J Haematol. 2005;131(3):400-2
  2. Maghzal GJ. ,Brennan SO ,FELLOWES AP. ,Spearing RL ,George PM
    ",Familial hypofibrinogenaemia associated with heterozygous substitution of a conserved arginine residue; Bbeta255 Arg-->His (Fibrinogen Merivale).
    Biochim Biophys Acta. 2003;1645(2):146-51
  3. FELLOWES AP. ,Brennan SO ,George PM
    ",Identification and characterization of five new fibrinogen gene polymorphisms.
    Ann N Y Acad Sci. 2001;936:536-41
  4. Brennan SO ,Wyatt JM. ,FELLOWES AP. ,Dlott JS. ,Triplett DA. ,George PM
    ",Gamma371 Thr-->Ile substitution in the fibrinogen gammaD domain causes hypofibrinogenaemia.
    Biochim Biophys Acta. 2001;1550(2):183-8
  5. Brennan SO ,FELLOWES AP. ,George PM
    ",Molecular mechanisms of hypo- and afibrinogenemia.
    Ann N Y Acad Sci. 2001;936:91-100
  6. Stott MK. ,FELLOWES AP. ,Upton JD ,Burt MJ. ,George PM
    ",Correction for Stott et al.: simple multiplex PCR for the simultaneous detection of the C282Y and H63D hemochromatosis (HFE) gene mutations
    Clin Chem. 2000;46(2):308-9
  7. Brennan SO ,FELLOWES AP. ,Faed JM. ,George PM
    ",Hypofibrinogenemia in an individual with 2 coding (gamma82 A-->G and Bbeta235 P-->L) and 2 noncoding mutations.
    Blood. 2000;95(5):1709-13
  8. FELLOWES AP. ,Brennan SO ,Holme R. ,Stormorken H. ,Brosstad FR. ,George PM
    ",Homozygous truncation of the fibrinogen A alpha chain within the coiled coil causes congenital afibrinogenemia.
    Blood. 2000;96(2):773-5
  9. Stott MK. ,FELLOWES AP. ,Upton JD ,Burt MJ. ,George PM
    ",Simple multiplex PCR for the simultaneous detection of the C282Y and H63D hemochromatosis (HFE) gene mutations.
    Clin Chem. 1999;45(3):426-8
  10. Brennan SO ,FELLOWES AP. ,George PM
    ",Albumin banks peninsula: a new termination variant characterised by electrospray mass spectrometry.
    Biochim Biophys Acta. 1999;1433(1-2):321-6
  11. FELLOWES AP. ,Brennan SO ,Ridgway HJ. ,Heaton DC. ,George PM
    ",Electrospray ionization mass spectrometry identification of fibrinogen Banks Peninsula (gamma280Tyr-->Cys): a new variant with defective polymerization.
    Br J Haematol. 1998;101(1):24-31
  12. Ridgway HJ. ,Brennan SO ,FELLOWES AP. ,George PM
    ",Rapid detection of the fibrinogen A alpha 16Arg --> His mutation.
    Clin Chem. 1997;43(11):2184-6
  13. Brennan SO ,FELLOWES AP.
    ",Albumin Hawkes Bay; a low level variant caused by loss of a sulphydryl group at position 177.
    Biochim Biophys Acta. 1993;1182(1):46-50
  14. McCormick SP. ,FELLOWES AP. ,Walmsley TA ,George PM
    ",Apolipoprotein B-32: a new truncated mutant of human apolipoprotein B capable of forming particles in the low density lipoprotein range.
    Biochim Biophys Acta. 1992;1138(4):290-6
  15. Peach RJ. ,FELLOWES AP. ,Brennan SO ,George PM
    ",Albumin Rugby Park: a truncated albumin variant caused by a G-->C splice-site mutation in intron 13.
    Biochim Biophys Acta. 1992;1180(1):107-10
  16. Scrimshaw BJ. ,FELLOWES AP. ,Palmer BN. ,Croxson MS. ,Stockigt JR. ,George PM
    ",A novel variant of transthyretin (prealbumin), Thr119 to Met, associated with increased thyroxine binding.
    Thyroid. 1992;2(1):21-6
  17. FELLOWES AP. ,Murphy JM. ,Wesley AW. ,Dawson KP. ,George PM
    ",Molecular screening of cystic fibrosis patients.
    N Z Med J. 1991;104(921):415-6
  18. Heaton DC. ,FELLOWES AP. ,George PM
    ",Concurrence of hereditary spherocytosis and alpha thalassaemia
    Aust N Z J Med. 1991;21(4):485-6
  19. McCormick SP. ,FELLOWES AP. ,Brennan SO ,George PM
    ",Apolipoprotein E variation in patients with hyperlipidaemia: DNA and protein phenotyping.
    N Z Med J. 1989;102(877):534-6
    Information last updated on 29 October 2008